Regulatory ILCs don't rely on FOXP3
نویسندگان
چکیده
منابع مشابه
Increased CD127 expression on activated FOXP3+CD4+ regulatory T cells.
Regulatory T cells (Treg) are commonly identified by CD25 (IL-2R alpha) surface expression and/or intracellular expression of the FOXP3 transcription factor. In addition, Treg are also characterized by low CD127 (IL-7R alpha) expression when compared to conventional T cells and their biology in the periphery is considered essentially independent of IL-7. We further investigated CD127 expression...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2017
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri.2017.107